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ZyO3™

Omega-3 fatty acids are important structural and functional components of human tissues. Among the long-chain Omega-3 fatty acids, EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are particularly well studied for their roles in cell membranes and lipid mediator pathways.¹,²

DHA is highly concentrated in neural and retinal membranes, where it contributes to membrane structure and function.²,³ EPA and DHA also participate in pathways involved in inflammatory signalling and resolution.⁴

ZyO3™ provides a concentrated source of EPA and DHA in a convenient softgel format. The product contains 360 mg EPA + 240 mg DHA per softgel, as declared on the current product pack. 

Each softgel contains:

  • Fish Oil
  • Capsule Shell: Gelatin
  • Purified Water
  • Humectants: INS 422 & INS 420(ii)
  • Preservative: INS 218
  • Artificial Flavouring Substance: Ethyl Vanillin

Allergen: Contains Fish. 

  • Concentrated EPA + DHA

ZyO3™ provides 360 mg EPA and 240 mg DHA per softgel, delivering a concentrated source of long-chain Omega-3 fatty acids.

  • Cardiovascular Wellness

EPA and DHA have been extensively studied for their relationship with cardiovascular outcomes and lipid metabolism. Evidence from randomized trials suggests that Omega-3 fatty acids can influence several cardiovascular outcomes, although effects vary according to formulation, dose and population.⁵

  • Brain Function

DHA is highly enriched in neuronal membranes and contributes to the structural and functional properties of the brain.²,⁶ Human supplementation studies, however, show that cognitive benefits are not uniform across all populations; therefore, ZyO3™ should be positioned as nutritional support for normal brain function, rather than as a cognitive treatment.⁶,⁷

  • Vision Health

DHA is a major structural lipid of retinal photoreceptor membranes and plays an important role in retinal structure and function.³

  • Joint Support

EPA and DHA influence inflammatory pathways and have been studied in people with inflammatory joint conditions. Meta-analyses of randomized trials have reported improvements in selected joint-related outcomes, although results should not be interpreted as treatment of arthritis.⁴,⁸

  • Healthy Ageing

DHA is particularly concentrated in the brain and retina, and Omega-3 status has been investigated in relation to brain health and age-related cognitive changes.²,⁶,⁹ The evidence does not support positioning Omega-3 supplementation as a treatment for age-related cognitive disease; the appropriate positioning is nutritional support as part of healthy ageing.

  • EPA – 360 mg: Incorporated into cell membranes and participates in the formation of lipid mediators involved in inflammatory signalling and resolution.
  • DHA – 240 mg: Highly concentrated in neuronal and retinal membranes, contributing to their structural and functional properties.
  • Other Omega-3 Fatty Acids – 400 mg: Contribute to the overall Omega-3 fatty-acid profile formulation.
  • Fish Oil: Provides the principal source of EPA and DHA in ZyO3™.
  • Total Omega-3 fatty acids: 1000 mg, comprising 360 mg EPA, 240 mg DHA, and 400 mg other Omega-3 fatty acids.
  • Recommended Usage Level:

Take one softgel daily, or as suggested by a Doctor or Dietician.

  • Duration of Usage:

Consume as advised by a Doctor or Dietician.

  • Route: Oral consumption.

The current ZyO3™ label specifies one capsule daily or as suggested by a Doctor or Dietician. 

  • Not for medicinal use.
  • This product is not intended to diagnose, treat, cure or prevent any disease.
  • This product should not be used as a substitute for a varied diet.
  • Pregnant and lactating women and people with any medical condition should consult a Doctor or Dietician before consuming this product.
  • Do not exceed the recommended daily usage.
  • In case of accidental overdose, contact a Doctor or Dietician.
  • Allergen: Contains Fish.
  • Keep out of reach of children. 


  • Nutritional Information

Serving Size: 1 Softgel

Servings Per Container: 60

Energy: 9.86 kcal

Protein: 0.05 g

Carbohydrate: 0 g

Total Sugars: 0 g

Total Fat: 1 g

Saturated Fat: 0.2 g

Trans Fat: 0 g

Cholesterol: 0 mg

Omega-3 Fatty Acids: 1000 mg

EPA: 360 mg

DHA: 240 mg

Other Omega-3 Fatty Acids: 400 mg

The above values reproduce the current ZyO3™ pack declaration.


  • Storage

Store in a cool, dry and dark place. Keep the container tightly closed after every use. Do not use if the seal is broken. Store out of reach of children.

  • Available Size

60 Softgels

The information provided on this page is intended for general nutritional and educational purposes and should not be considered a substitute for professional medical advice.

ZyO3™ is a nutraceutical and not a medicine. It is not intended to diagnose, treat, cure or prevent any disease. Individual nutritional requirements vary. Consult a qualified Doctor or Dietician for personalised advice, particularly during pregnancy, lactation or in the presence of a medical condition.

  1. Valentine RC, Valentine DL. Omega-3 fatty acids in cellular membranes: a unified concept. Prog Lipid Res. 2004;43(5):383-402.
  2. Rapoport SI, Ramadan E, Basselin M. Docosahexaenoic acid and the brain—what is its role? Prostaglandins Leukot Essent Fatty Acids. 2011;85(5):229-238.
  3. SanGiovanni JP, Chew EY. The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. Prog Retin Eye Res. 2005;24(1):87-138.
  4. Calder PC. Omega-3 fatty acids and inflammatory processes: from molecules to man. Biochem Soc Trans. 2017;45(5):1105-1115.
  5. Khan SU, Lone AN, Khan MS, Virani SS, Blumenthal RS, Nasir K, et al. Effect of omega-3 fatty acids on cardiovascular outcomes: a systematic review and meta-analysis. EClinicalMedicine. 2021;38:100997.
  6. Dighriri IM, et al. Effects of omega-3 polyunsaturated fatty acids on brain functions: a systematic review. Cureus. 2022;14(11):e31613.
  7. Cooper RE, Tye C, Kuntsi J, Vassos E, Asherson P. Omega-3 polyunsaturated fatty acid supplementation and cognition: a systematic review and meta-analysis. J Psychopharmacol. 2015;29(7):753-764.
  8. Li Y, et al. Effects of omega-3 supplementation on lipid metabolism, inflammation, and disease activity in rheumatoid arthritis: a meta-analysis of randomized controlled trials. Clin Rheumatol. 2024.
  9. Alex A, Abbott KA, McEvoy M, Schofield PW, Garg ML. Long-chain omega-3 fatty acids and cognitive decline in non-demented adults: a systematic review and meta-analysis. Nutr Rev. 2020;78(6):451-466.


FAQ

ZyO3™ is a high-strength Omega-3 fish oil nutraceutical providing 1000 mg fish oil per softgel, including 360 mg EPA and 240 mg DHA.

EPA and DHA are long-chain Omega-3 fatty acids. They are incorporated into cell membranes and participate in biological pathways involved in cardiovascular, neural, retinal and inflammatory processes.¹–⁴

EPA and DHA have different but complementary biological roles. DHA is particularly concentrated in neural and retinal tissues, while EPA is involved in membrane composition and lipid mediator pathways.²–⁴

EPA and DHA have been extensively investigated for cardiovascular effects. Clinical evidence indicates that Omega-3 supplementation can affect cardiovascular outcomes, although benefits vary by dose, formulation and patient population.⁵

DHA is an important structural component of neuronal membranes. However, supplementation does not necessarily improve cognition in every healthy individual. ZyO3™ should therefore be positioned as nutritional support for normal brain function, not as a treatment for cognitive disorders.²,⁶,⁷

Yes. DHA is highly concentrated in retinal photoreceptor membranes and contributes to retinal structure and function.³

EPA and DHA influence inflammatory pathways and have been studied for joint-related outcomes, particularly in inflammatory joint conditions. Evidence suggests potential benefit for selected outcomes, but Omega-3 should not be presented as a treatment for arthritis.⁴,⁸

ZyO3™ is a nutraceutical intended for adults as part of a balanced diet. Pregnant or lactating women and people with medical conditions should consult a Doctor or Dietician before use.

Yes. ZyO3™ contains fish oil and the product carries the declaration “Contains Fish.”